Basic Molecular Information

Basic Information

DICL ID
DICL_CP_0356667
PubChem CID
Molecular Formula
C22H30NO4+
Molecular Weight
372.485 g/mol
Synonyms/Alias
[N-Me-laudanosine; N-methyl-laudanosine; CHEMBL215370; CHEMBL1182154; BDBM50199404; 1-(3;4-Dimethoxy-benzyl)-6;7-dimethoxy-2;2-dimethyl-1;2;3;4-tetrahydro-isoquinolinium iodide; 1-(3;4-Dimethoxy-benzy...
InChI Key
RVBHVIRGZXRPRX-SFHVURJKSA-N
InChI
InChI=1S/C22H30NO4/c1-23(2)10-9-16-13-21(26-5)22(27-6)14-17(16)18(23)11-15-7-8-19(24-3)20(12-15)25-4...
IUPAC Name
(1S)-1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-2,2-dimethyl-3,4-dihydro-1H-isoquinolin-2-ium
CAS Number
64228-81-5

Structure Information

Chemical Structure Visualization

SMILES Notation
2D Molecular Drawing
Carbon (C)
Hydrogen (H)
Oxygen (O)
Nitrogen (N)
Sulfur (S)
SDF

27 29 0 0 0 0 0 0 0 0999 V2000
1.3951 -0.6763 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
0.2428 -1.6366 0.0000 N 0 0 0 0 0 4 0 0 0 0 0 0
-0.5115 -2...

Experimental Data

Activity Data

Target Ion Channel
Small conductance calcium activated potassium channel protein 1/2/3
Uniprot Accession Number
Function
Blocker
Species
Rattus norvegicus (Rat)
IC50
N/A (Not available)
EC50
N/A (Not available)
Ki
Ki: 15000 nM
Kd
N/A (Not available)
Inhibition
N/A (Not available)

Experimental Conditions

pH
pH 7.4
Holding Potential
Not mention mV
Temperature
Room Temperature
Test Method
Patch-clamping
Test Species
Not specified

Binding Information

Binding Site
Not specified
Binding Site Residue
Not specified

Disease Information

Related Disease
Not specified

References

URL
N/A (Not available)
PMID
Patent
N/A (Not available)

Computed Properties

Heavy Atom Count
27
Rotatable Bonds
6
logP
3.6373
Complexity
106.2164
TPSA (Ų)
36.92
H-Bond Donors
0
H-Bond Acceptors
4
Ring Count
3
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